Covid-19 vaccine efficacy after first dose pfizer moderna
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Covid-19 vaccine efficacy after first dose pfizer moderna - sorry, that
VE of partial 1-dose and complete 2-dose vaccination in this population is comparable to that reported from clinical trials and recent observational studies, supporting the effectiveness of mRNA COVID vaccines against symptomatic disease in adults, with strong 2-dose protection.Controls were frequency matched to case-patients aiming for a ratio of three controls per case-patient by site and week of test. Vaccination records, including dates and type of COVID vaccine received, were obtained from occupational health or other verified sources e.
HCP were defined as unvaccinated if they had not received any COVID vaccine doses or had received their first dose after the test date. The interval of 0—13 days from receipt of the first dose was defined as the time before first dose vaccine effect.
The effectiveness of a single dose was measured during the interval from 14 days after the first dose through 6 days after the second dose. Because of the potential for vaccine-related reactions to influence HCP testing behaviors, sensitivity analyses of single-dose VE were conducted 1 excluding participants tested within 0—2 days of receiving the second dose and 2 measuring VE before receiving the second dose. Because the single-dose effectiveness estimates in this and other studies were based on a short follow-up, the duration of this level of protection from a single dose is unknown.
The findings in this report are subject to at least six limitations. Scientists are particularly concerned about the Delta variant because it appears to be especially contagious.
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